Friday, November 29, 2019

USA- Spain an Example by

USA- Spain Spain is as diverse as any other country, especially for non-natives. However, several principles of human resources still apply to companies based in Spain where employees are most likely Spanish. These general principles along with specific ones can help improve job satisfaction, improve motivation, and increase performance in all departments. Need essay sample on "USA- Spain" topic? We will write a custom essay sample specifically for you Proceed First, it should be understood how diversity should be put to an advantage. Differences among employees are nothing new to international businesses. Thus, the differences should be identified and all efforts should be put in understanding them and putting them in their proper perspectives. For instance, adjusting in the time differences in the work schedules of workers in Spain should be made. The first consideration is that superiors should understand the culture of siesta. Because workers used in this culture may find it difficult to go back to work with the same level of energy that they have in the morning, managers should promote activities that will perk them up when they go back to work in the afternoon after the siesta break. Siesta is not the only cultural difference that Spain has over the United States and other countries. The Geert Hofstede Cultural Dimensions (Hofstede, 2003) indicate some job-related factors that make Spanish workplaces different from those in the United States. First, the power distance index in Spain is greater than in the United States. This shows that hierarchy is important for Spanish workers. Thus, line of functions if there are any should be closely observed. Superiority should be well respected and job descriptions should be followed. Giving regard to hierarchy is important for the Spanish so non-natives should be sensitive about it to avoid offending them. Americans are more liberal than the Spanish. This is evident in the high margin that it maintains over Spain in terms of individualism. Thus, American workers can be used to speaking out and speaking up, while the Spanish can keep restraint and avoid deviance. This can pose a problem for Americans new to Spain especially in the workplaces where team work is essential. (Hofstede, 2003) In view of this, Americans should not take it negatively if they find it hard for their Spanish workers to contribute actively at work. While Spanish workers can also exercise initiative, it is not a general practice for them to precede the initiative of their superiors because, as mentioned above, they highly regard hierarchy and power distance. Americans, thus, should mean well by being more encouraging to their Spanish workers and giving constructive criticism to their initiatives. It should also be noted well that the lack of individualism can make the Spanish sensitive with outright negative criticism. Unlike in the United States, Spanish workers may not take criticism told straight up easily. Americans in Spain should know this so that they may avoid this which can greatly affect the work performance of their workers. Where history was discriminative and regarded women as second-class citizens everywhere once, Hofstede (2003) claims that masculinity is greater in the United States than in Spain. This may induce the fact that American workplaces can be more male-dominated than Spanish workplaces. However, it should not be concluded that American workplaces are more discriminative. In fact, American firms are drastically enforcing measures to avoid all forms of discrimination including against women. In view of an American in a Spanish workplace, however, care should be taken that discrimination against women that may be normal in a United States setting is avoided. In fact, discrimination of any form should be eliminated at any angle. It should be noted that diversity does not make a specific culture more superior than others. This will foster good relations among employees and employers however diverse the setting may be. Americans are individualistic, and so it follows that they can be adventurous as well. Hofstede (2003) showed that the Spanish avoid uncertainties and can play things safely more than their American counterparts. This is essential especially for stakeholders and high-ranks. Knowing that the Spanish can be less adventurous, they should make sure that every step they take in the business that they are handling are carefully studied and backed up with relevant and updated data. This lessens the risks in their decisions which may repel Spanish partners and officers from supporting their proposals. If they show that every single detail of the proposal has been studied, they are more likely to endorse the proposal and enforce it. As with workers, managers should show workers how a decision has been made, and how it can affect the workers and the company both positively and negatively. Laying the cards straight will enable the workers to get a view of the situation and clarify doubts and qu estions that they may have early on. As risk-taking behavior is evidently essential for businesses to maintain their competitive edge, Americans should be sensitive about the play-safe behavior of the Spanish and should work around it. The more one adheres to the culture of one country, the easier it is for him to blend in. Reading about the country and its people as well as seeking guidance from a native can very well improve ones staying power in a Spain-based company. Avoiding saying words that one does not understand is one key. The Spanish uses a language that is totally different from that of Americans, and so it should be understood that using the language should be taken with care. This will dispel slip-of-the-tongues and mispronunciations which can be funny and worse offensive to native speakers of the language. Dressing is another consideration. While corporate dressing is a universal language, it can still be highly variable in consideration of the climate changes in the country and the comfort of the people there. Thus, while one is get used to specific clothing items in his centrally air-conditioned office, if it does not fit well in the workplace in Spain (even if it is equally air-conditioned and the position and company is the same), deviant clothes should go and replaced with ones which will allow one to blend in. Diversity is a challenge that multinational companies face every single day. Yet, this should not stifle companies from prospering. Again, fostering these differences for the advantage of the company is the key to creating a homogenous group of workers who can co-exist despite major incompatibilities. In the end, it will appear true that managing diversity in the workplace is the only way that companies can penetrate the global business scene. References Hofstede, G. (2003). Geert Hofstede cultural dimensions. Retrieved June 7, 2007, http://www.geert-hofstede.com/hofstede_dimensions.php This essay is written by top academic experts from our essay writing service (USA).

Monday, November 25, 2019

Concepts and Styles of the Leadership

Concepts and Styles of the Leadership Leadership refers to the process of influencing and managing people in order to achieve intended outcomes. Leaders adopt different leadership styles depending on prevailing circumstances. Leadership styles base on different leadership concepts. However, certain concepts apply to all styles.Advertising We will write a custom essay sample on Concepts and Styles of the Leadership specifically for you for only $16.05 $11/page Learn More For example, action is an important aspect of effective leadership. Research has revealed that leaders who focus on personal development and growth not only change themselves but also lead their organizations to great levels of success. The seven action logics include Achiever, Expert, Opportunist, Diplomat, Alchemist, and Strategist action logics (Rooke and Torbert, 2005). Microsoft founder Bill Gates, is an exceptional leader who has transformed the technology industry through his visionary leadership style and great skills. Ac cording to Rooke and Torbert (2005), only Individualist, Strategist, and Alchemist action logics enable leaders to transform organizations through sustained innovation. Bill Gates transformed the world of technology through his innovativeness. He believed that innovation is an important condiment of organizational success and transformation. When he developed the windows software, he maintained quality by incorporating innovative ideas into subsequent versions of the software. As such, he continued to develop improved versions of windows during his term at Microsoft. Innovation is a characteristic of the Strategist action logic. Gates’ strategy was to incorporate innovation into the operations of Microsoft and make it part of its organizational culture. This has enabled Microsoft to withstand the unpredictable and rapidly changing technology market. Strategists capitalize on organizational constraints and perceptions in order to achieve personal development (Rooke and Torbert , 2005). In addition, they are able to lead people in ways that help them to overcome resistance to change. Gates used his strength as an effective leader to introduce change at Microsoft despite resistance and numerous obstacles. Alchemist action logic involves creativity, open mindedness, and deviation from commonplace attitudes and values (Rooke and Torbert, 2005). Bill Gates valued change. When he was at the helm of Microsoft, he ensured that the organization changed its operations in order to adapt to changes in technology. This is evident from the stability and success that Microsoft has enjoyed for many years despite obstacles such as patent lawsuits and stiff competition. The leadership style of Gates has enabled Microsoft to be one of the market leaders in technological innovation for many years. However, after his departure, the company was overtaken by emerging technology-oriented enterprises. This was because the new leader failed to adopt a similar action logic that Gat es had adopted.Advertising Looking for essay on business economics? Let's see if we can help you! Get your first paper with 15% OFF Learn More Achievers realize organizational goals through teamwork and balancing their roles as leaders and managers (Rooke and Torbert, 2005). In addition, they are action and goal oriented. Bill Gates is an action and goal oriented leader. He believes that well-defined goals are necessary for achievement of organizational success. As the CEO, he ensured that Microsoft maintained creativity and innovation by reiterating the importance of teamwork. Teamwork encouraged open sharing of ideas and knowledge, which enhanced innovation and creativity. Below-average leadership is characterized by Diplomat, Opportunist, and Expert action logics (Rooke and Torbert, 2005). For example, opportunists are egocentric and manipulative. As CEO, Gates never manipulated his employees and never allowed his ego to take a toll on his organization. M oreover, he delegated leadership roles. This is contrary to opportunists’ behavior of controlling people and treating them like objects. Unlike opportunists who reject feedback, Gates valued feedback because it was the foundation of innovation at Microsoft. Diplomats avoid conflicts and are resistant to change (Rooke and Torbert, 2005). This is in contrast to the leadership style of Gates. He believed in change and incorporated it into Microsoft’s organizational culture in order to ensure organizational success. Rooke, David, and Torbert, William. Seven Transformations of Leadership. 1 April. 2005. Web. https://hbr.org/2005/04/seven-transformations-of-leadership.

Thursday, November 21, 2019

Immigrants and nativism Essay Example | Topics and Well Written Essays - 250 words

Immigrants and nativism - Essay Example This political party would oppress any immigrants for the existing job for the Native Americans (Bennett 179). During the potato famine in the mid 19th century, a huge wave of nativism took part in unite states after the migration of Irish Catholics to the country. Petitions to the congress from the northeastern state suggesting that the immigrants right to vote be limited. The Irish Catholics were barred from holding any public office across many states when the constitution became the law of the land in 1806. In Massachusetts and other colonies by the 1870s, a celebration of Guy Fawkes Day was done by burning the pope in effigy. Allegiance to the pope was viewed to bring political unrest in America by the natives. A national nativist movement was organized by November 1837 by anti-Catholics. With the increase in numbers of immigrants between 1820s-1850s, there was reinforcement of economic, social, and political concern in New York and other points was done. A native majority select committee in the House of Representatives endorsed legislation extending the naturalization period for all the immigrants especially the Irish Catholics who they deemed as uneducated, superstitious and dominated by their priests (Bennett, 174). Though, with much support, the legislation did not pass. A lot of legal restriction soon followed all trying to oppress the immigrants and even trying to get rid of

Wednesday, November 20, 2019

The Galapagos Island Tortoise Essay Example | Topics and Well Written Essays - 750 words

The Galapagos Island Tortoise - Essay Example The Galapagos Tortoise are the largest living breed of tortoises in the world. They inhabit the nine islands of the Galapagos archipelago. While Charles Darwin was the first to research these animals, they were actually discovered by a Spanish explorer in the 1500’s. â€Å"Galapago† means tortoise in Spanish and most likely derives from the word saddle. The Galapagos turtles have a distinctive shell that is in the shape of a saddle. The size of these creatures is what sets them apart from other species. The adults can weigh over 660 lbs while they are approximately 4 feet long. Scientists have not figured out a maximum life expectancy for the tortoise however they are expected to live around 200 years. They are believed to belong to one species called Geochelone elephantopus, with approximately 14 different sub speciesThe arrival of the Galapagos tortoises is thought to be descended from a common ancestor that arrived from the mainland. They are capable floating quite e asily on the water. Scientists believe that the original colonist of tortoise washed aboard one island then its descendants were dispersed around the other islands-floating on the ocean currents. In the 1600’s buccaneers used the Galapagos Islands as a home port to repair their boats before attacking Spanish colonies on the South American mainland. They collected the tortoises and stored them aboard their ships because they lived for a long while. They were eaten as a source of food as well as killed for their turtle oil. The early settlers hunted them for their meat up through the 1800’s. ... If they feel threatened by another animal, they withdraw its head, neck and forelimbs into its shell for protection. Sometimes this is not enough as the top of their shell opening can leave a gap. Originally, this was never an issue because there were no native predators on the Galapagos Islands. It is only when settlers introduced domesticated animals that went wild that they became susceptible. And of course, they were hunted by the settlers for food. The conservation efforts of the tortoise populations still face challenges today. Rats, dogs, and pigs eat the eggs and young tortoises. Goats are in direct competition with them when acquiring food so many of them devastate the vegetation. Also, cattle, donkeys, and horses trample the ground squashing the tortoises nests. Efforts have been made to safeguard tortoises nests. One such example is that eggs are collected in the wild and incubated at the Charles Darwin Research Station. After they hatched, they would remain under vigil until they were large enough to fend off attacks from rats, dogs, and pigs. There have also been campaigns to eradicate the wild animals that pose a threat to the tortoise. These methods of preserving the giant tortoises have worked really well as it is predicted that only 120 turtles have been killed over the last 17 years. With all the work that has been put into the effort to keep the main attraction of the Galapagos islands from becoming extinct, there is still more work to be done. Many of the animals that are not native to the island should be removed in the effort to keep the these fascinating turtles alive and well. When Charles Darwin made a trip to the Galapagos Islands, he found a huge

Monday, November 18, 2019

Forms and Substance Dualism Essay Example | Topics and Well Written Essays - 2000 words

Forms and Substance Dualism - Essay Example If, conversely, dualism can be convincingly maintained, then our evidence obtained from studies of the brain would simply not suffice in gaining any form of insight into the human mind. Dualism is a logical necessity: sustained as a question that does not need to be answered as it can be fulfilled a priori, owing to the fact that humans have the ability to seek introspection regularly. (Almog, 129-34) Indeed, we experience the separation between our body and mind, which would support the notion that they are separate entities and empirical evidence is not required to prove such a concept. However, this does not mean that dualistic theory is foolproof: for example, can our experience be enough to prove such a concept Indeed, many philosophers are not in favor of dualistic ontology. The first classical representation of dualism can be recognized in Plato's work; more specifically originating in The Phaedo. Interestingly, in dualism, 'mind' is contrasted with 'body', but in different historical periods, different aspects of the mind have been the center of attention. For example, in the classical period it was the intellect of the mind, which was considered to be the crux of what separated us from the physical. However, from Descartes onwards, the opposition to materialism came from our apparent 'consciousness' and experience of 'sensation'. The emphasis on intellect is certainly echoed in Plato's work: as he believed (as did many other Greeks) that the body was a prison for the intellectual soul. Indeed Plato believed that the true substances are not physical bodies, which are ephemeral, but the eternal Forms of which bodies are imperfect copies. He came up with the idea of a realm of "Forms" and said that intellect was immaterial, for it does not last you, the refore Forms are immaterial, and thus intellect must link to those that it apprehends. He then continued to say that such a link forced the soul to want to leave the body to enter a realm of Forms. In his later writings, The Republic, Plato furthered his ideas on Forms and the soul; he claimed that not only was the soul the true form but belonged to a higher status within reality than the body did, and that the soul was a separate, immortal substance. Plato's study of dualism in The Phaedo was indeed complex, and more a metaphysical study regarding the imprisoned soul. However, it can be seen, especially amongst his writings in The Republic, that Plato was clear on his belief that the body and soul were separate entities, forming the base for philosophical extensions in more recent times. Continuing from Plato, St Thomas Aquinas extended earlier works on dualism in his endeavor to unite philosophy with proof of God. Aquinas agreed with the Aristotelian notion that when the soul entered the body it animated it and gave it life; calling it anima. Moreover according to Aquinas, the soul operates independently of the body and it cannot decay; for only things that can break into parts can decay, Thus, following Aquinas' argument, the soul is able to survive death. He also said that through

Saturday, November 16, 2019

Treatments of Parkinsons Disease

Treatments of Parkinsons Disease Parkinsons disease is a neurological condition that affects the sufferers mobility and speech. It affects the central nervous system, leading to a persons inability to control muscles throughout the body. It is a disease whose treatment does not intend to cure it but instead, aims at controlling its manifestation. There are various ways in which this can be done. It may involve the use of drugs or the performance of surgery. Doctors strongly recommend exercise to try to keep muscles strong. It progresses gradually or severely from the early stages with mild symptoms to later stages with severe symptoms. The disease is a result of lowered formation and action of dopamine which is produced by the dopaminergic neurons found in the brain. This knowledge led to the formation of drugs that will either increase the formation or mimic the actions taken by dopamine in the brain. This was important because an increase in the levels of dopamine would lead to a reduction of the effects of the disease. All the drugs used to control the disease include dopamine as their main active agent regardless of how it works. Depending on which class of drugs it belongs to, it may either mimic or produce dopamine. Among the earliest forms of treatments are the anticholinergics. These were used even before the introduction of Levodopa, which is now the most widely used drug. The anticholinergics had very little benefits when compared to the harmful side effects caused by usage. The side effects include having a dry mouth, urine retention (which especially occurs among men), and very severe constipation and nausea. There are some other side effects that occur that are more serious and are among the major reasons why the use of these drugs has become minimal. These include confusion, memory loss, and hallucination (http://www.mayoclinic.com). The realization that the benefits seen were much less than the side effects it causes has led to the reduction of its prescription. Since some anti-depressants and antihistamines tend to have almost the same effect as the anticholinergics, doctors will prescribe them to older people who are suffering from this terrible disease. Once an individual experiences any of the serious severe symptoms, it is advised that the use of the drug be stopped immediately. Levodopa is a drug that was introduced in 1967 and is currently the most commonly used drug. It is most commonly referred to as Sinemet and is used to help restore ones control over ones muscles. Levodopa is referred to as the gold standard of Parkinsons treatment because it is usually used as the first line of defense. The reason a sufferer of Parkinsons cant just take Dopamine itself is because Dopamine cannot breakthrough the blood-brain barrier. Levodopa can get through this barrier and is converted to Dopamine once it reaches the brain. It therefore increases the level of Dopamine and counters the effects of the disease. The conversion to Dopamine is what leads to the positive effects that a patient experiences when using the drug (Henkel). Levodopa however has very serious side effects which include nausea and dyskinesias (involuntary movement). This occurs because only a small percentage of the drug actually reaches the brain to be transformed into Dopamine. The rest of it is transformed into dopamine in the body. It therefore becomes necessary to use Carbidopa, which delays the metabolism of Levodopa until it reaches the dopaminergic neurons in the brain. The combination helps reduce the side effects caused by the drug. Carbidopa delays the metabolism of Levodopa, keeping it from metabolizing in the body. This helps to greatly reduce the side effects felt by the user. The other problem posed by the use of this drug is that its dosage needs to be increased over time. It has also been observed to work on and off without any explanation or reason. This makes it unreliable because its effects are not constant, and at times the patient gets violent attacks while still under medication. The various side effects and unreliability of levodopa leads to the necessity to combine it with various other drugs to make it more effective. Some of these drugs can be used on their own while others actually require to be used with the Levodopa-Carbidopa combination. A cluster of drugs called Dopamine agonists are usually used in a combination with the Levodopa-Carbidopa drugs. They can however also be used on their own if the disease has not greatly progressed. Also, it is recommended that these drugs only be used alone in young adults. This class of drugs does not produce or help in the production of dopamine but instead imitates the effects that Dopamine has in the body. They tend to act on behalf of Dopamine (http://www.mayoclinic.com). This class of drugs include; Apokyn, Requip, Parlodel and Mirapex. Parlodel has been used very little of late. This is because it had very serious side effects that endangered the patient more than it benefited him/her. It would cause inflammation in the lungs and/or heart valves of the user and would lead to further deterioration of the patients health. In general this class of drugs has side effects that are almost similar to those of carbidopa-levodopa but with slight differences. The effects of having involuntary movement are reduced while those of hallucinations and/or sleepiness are increased. The drug Mirapex takes up the role of dopamine in the body as it is one of the dopamine agonists. When it is used in the absence of Levodopa-Carbidopa, it causes a 30% improvement in the health of the patient. When used in combination, it is able to reduce the intake of the Levodopa dosage by about 25%. Requip is also a dopamine agonist that can also be used either alone or with Levodopa. When used together with Levodopa, it can reduce the intake of Levodopa by around 31%. The reduction of Levodopa dosage decreases side-effects to the patient (Henkel). Catechol-o-methyltransferace inhibitors, which are usually abbreviated as COMT inhibitors, are used to block the enzymes that break down the Levodopa into Dopamine before it reaches the brain. They can be used in combination with the Carbidopa-Levodopa therapy. The two main COMT inhibitors are Tasmar and Entacapone. Tasmar is rarely used because of its severe impact on the health of the user. It causes severe liver damage and hence is only used as a last resort if the patient has failed to respond to any other therapy (http://www.mayoclinic.com). Entacapone does not have side-effects as severe as those of Tasmar and is therefore recommended over Tasmar. Its major side-effect is the involuntary movements experienced by the user. It works in conjunction with the Carbidopa-Levodopa therapy by increasing their availability. This is done by blocking the enzymes that break down the substance into Dopamine until the drug is already in the brain. This then means that the effects of Levodopa-Carbidopa are prolonged because they occur only in the brain. Stalevo, another drug, is the result of a combination of Carbidopa, Levodopa and Entacapone. Selegiline, also referred to as Eldepryl, is another drug that can either be used with or without the presence of Carbidopa-Levodopa therapy. It works by preventing the metabolism of Dopamine. It does this by slowing down the activity of one of the enzymes that metabolize Dopamine. This is the monoamine oxidase B which is abbreviated as MAO-B. The use of Selegiline has other positive effects like delaying the need of Carbidopa-Levodopa. When combined with Carbidopa-Levodopa it improves the effectiveness of the drug. It can however have some adverse toxic reactions when combined with Demerol which is a narcotic drug. Apart from ingesting drugs, they can be administered through the skin through the use of a silicon-based patch. Rotigotine is a dopamine agonist drug that can be administered through the skin, but can only be used in the early stages of the disease. This is called Neupro-rotigotine transdermal system. The patch has to be changed every 24 hours. It works by stimulating the Dopamine receptors in the body. Its side-effects include skin reaction where the patch is, hallucinations, insomnia, drowsiness, sleep-attacks, nausea, vomiting and the most severe is the reduction in blood pressure once the person stands up (http://www.fda.gov). Amantadine is another drug that is used in treatment of Parkinsons disease but its use was discovered by accident. Initially it was created to be an antiviral used in the treatment of influenza and was approved as such in 1976 by the Food and Drug Administration. It was however discovered to provide short term relief when used alone in the early stages of the Parkinsons disease. When it is combined with Carbidopa-Levodopa it can be used by those in the later stages. It has side effects that mostly involve swelling of the ankles and turning skin color purple (http://www.mayoclinic.com). In every human beings body, there is the presence of coenzyme Q10 which is produced by the mitochondria. This enzyme is used in the transport of electrons so that they can gain energy from the oxygen inhaled. This is done in the process called cellular respiration. The levels of this enzyme are very low in those suffering from Parkinsons disease. These people can therefore benefit greatly by having more of this enzyme. This can only be achieved by taking supplements which can be bought from a pharmacy. This aids in helping to slow down the onset of the disease. Apart from the use of drugs, there are various surgeries that can be used to control the effects of the disease. One of the surgeries is pallidotomy which involves the destruction of a small bit of the globus pallidus. Doctors believe all people who are suffering from Parkinsons have an overactive globus pallidus. The procedure is done by drilling a small hole in the skull and using an electric probe to kill part of the pallidus. It can only be done when the patient is sedated but awake so the doctor can judge the patients reactions to stimuli. There is a globus pallidus on each side of the brain, but the operation can only be done on one side at a time. Its side effects mostly involve impaired speech (http://www.fda.gov). Thalamotomy is another surgical procedure used in the control of Parkinsons disease. It is only performed on those patients who are experiencing tremors in either the hands or the arms that become too severe to handle. Usually the tremors are so bad they disable the person. It involves the destruction of a specific group of cells that are located in the thalamus in the brain. The surgery reduces or completely eliminates the tremors in around 90% of those who undergo the procedure (http://www.fda.gov). There is also the presence of a gadget that can be compared to the pacemaker used for cardio problems. It is known as the brain pacemaker (http://www.fda.gov). This form of therapy is referred to as Active Tremor Control Therapy. It involves the surgical implantation of an insulated wire to the brain. It is placed in the thalamus region of the brain, the subthalamic nucleus, and also the globus pallidus area of the brain. The whole system includes three components which are the: lead, extension and the neurostimulator. This system is referred to as Deep Brain Stimulation because it occurs directly inside the brain. A small hole is made in the skull and through it the lead is inserted into the brain. The lead is a very thin insulated wire. The tip of the lead is in contact with the area that has been targeted. Once it has been implanted, it is connected to the neurostimulator by the extension which is also an insulated wire (http://minds.nih.gov). The extension passes under the skin and moves from the head, to the neck, the shoulder and finally to where the neurostimulator is located. The neurotransmitter is located either under the collarbone, in the abdomen or the lower chest area just directly under the skin. The neurotransmitter involves a battery pack that sends electrical impulses to the brain. This is done through the extension and the lead. When the person is undergoing tremors, he or she is supposed to pass a handheld magnet over the location of the neurostimulator. The electrical impulses that are sent by the neurostimulator work by blocking the electrical signals that are the cause of the Parkinsons disease symptoms. They are dysfunctional brain signals and they are the cause of the tremors. This procedure is preferred because it does not destroy the nerve cells and when one wants to stop its use it is as easy as having the system surgically removed. Works Cited Deep Brain Stimulation for Parkinsons Disease Information. NINDS. 22 Nov. 2007 . Henkel, John. Parkinsons Disease: New Treatments Slow Onslaught of Symptoms. FDA. 22 Nov. 2007 . Neupro Patch for Parkinsons Approved. FDA. 22 Nov. 2007 . Parkinsons Disease: Treatment. MayoClinic. 22 Nov. 2007

Wednesday, November 13, 2019

You Must Depend Only on Yourself :: Arguementative

Depending on Yourself Have you ever been told something by somebody, acted upon what you were told, then found out what they told you was wrong? This just goes to show that you should never rely on anybody else's word. I have always been told that attitute is everything. If you want to do accomplish something, your attitute towards your goal is the most important factor in your success. However, my personal experiences say otherwise. In seventh grade P.E. class, I had taken up the attitute that P.E. is a waste of time, and was not motivated to actively exert effort in the class. This kept up throughout the year, and my grade at the end was a "B". The next year, I decided I had better change my ways. I made sure to show enthusiasm and effort throughout the year. My final grade this time? Still a "B". This has forever disheartened me from trying to get an A in P.E., since it seems that nothing you do can change your grade. Even if you change your attitute, the result can be the same. The necessity of self-reliance becomes more and more apparent if you start to search for examples. For instance, several of my friends had a certain teacher for a physics class, who was often wrong in his teachings, but unwilling to admit to his mistakes. They had to compare what he had taught them with information in other places, to make sure he wasn't teaching the lessons incorrectly. Due to his mistakes, they had to rely on themselves, not the word of the teacher. My parents always tell me that if I don't want homework to be such a chore, that I have to motivate myself. I took their advice with an open mind, and got myself motivated for a history essay. But when the time came to write it, it was just as bad as any other. You Must Depend Only on Yourself :: Arguementative Depending on Yourself Have you ever been told something by somebody, acted upon what you were told, then found out what they told you was wrong? This just goes to show that you should never rely on anybody else's word. I have always been told that attitute is everything. If you want to do accomplish something, your attitute towards your goal is the most important factor in your success. However, my personal experiences say otherwise. In seventh grade P.E. class, I had taken up the attitute that P.E. is a waste of time, and was not motivated to actively exert effort in the class. This kept up throughout the year, and my grade at the end was a "B". The next year, I decided I had better change my ways. I made sure to show enthusiasm and effort throughout the year. My final grade this time? Still a "B". This has forever disheartened me from trying to get an A in P.E., since it seems that nothing you do can change your grade. Even if you change your attitute, the result can be the same. The necessity of self-reliance becomes more and more apparent if you start to search for examples. For instance, several of my friends had a certain teacher for a physics class, who was often wrong in his teachings, but unwilling to admit to his mistakes. They had to compare what he had taught them with information in other places, to make sure he wasn't teaching the lessons incorrectly. Due to his mistakes, they had to rely on themselves, not the word of the teacher. My parents always tell me that if I don't want homework to be such a chore, that I have to motivate myself. I took their advice with an open mind, and got myself motivated for a history essay. But when the time came to write it, it was just as bad as any other.

Monday, November 11, 2019

The Things They Carried

Tim O’Brien’s novel, The Things They Carried, provides an incredible realization of what life was like for an American soldier who fought in Vietnam from perspectives before, during, and after the war. The story’s power draws you in. It makes the events in the story seem real and provides the reader with a sense of what it feels like to be one of the soldiers. O’Brien’s talent as a writer made a fictional story more than believable to the reader. When reading this book, the reader struggles with depicting what is factual and what is fictional. O’Brien provides this effect by blurring the line between reality and fantasy. The book recollects many stories from O’Brien’s own experiences as a soldier and includes fictional aspects to enhance the story and to help O’Brien get his point across. O’Brien teaches us in all of these stories that there is no difference between what is factual and what is fictional in war. By doing this, the reader experiences the feelings that O’Brien and his comrades felt. The Things They Carried describes what those men carried to battle and back home, both tangible and intangible. The novel questions what war is and what the individual soldiers received out of it. This novel is an eye opener. Any person’s perspectives on the war and its soldiers are most certainly to change after reading this book. The Things They Carried brings the Vietnam War to life like no civilian could have ever imagined. The things the soldiers carried in Vietnam were both tangible and intangible. The tangible items include the usual equipment that soldiers carry, but most important is the intangibles. This book emphasizes that the intangibles the soldiers carried influenced everything about their lives, before, during and after the war. These things included the mental and psychological weight carried by the soldiers. This weight included shame, horrid memories, death and destruction. It included relationships and personal trials and temptations. It also included the soldiers’ way of handling the war. Many soldiers described in the novel used things such as drugs, pain, or fantastical illusions to deal with the war. The author, who is the narrator, was against the war. The book displays the weight of the personal struggle that he felt as someone against what he was doing over there. Another aspect that the book describes is the inexperience that the soldiers carried. This came from their age. Most, including the author, were of 21 years of age or younger. They carried the weight of large futures being destroyed by their involvement in the war. All of these aspects put extreme emotional stress on the lives of these soldiers during and after the war. The author deals with his emotional dilemmas by wiring about the tragedies and emotions he and his comrades felt. The book is entirely based off of these things. Its purpose is to help those who were not there to understand what it felt like to be them and for us to never forget the things they carried. The Things They Carried is about death. It questions death. It asks what death feels like. It also answers these questions by pulling death up and bringing it back to life. It brings it back to life and tells its stories. These stories share with the reader what death feels like. They show the reader what death is like for you and those who care about you. The author includes this topic, because it relates to something important to him that he â€Å"carried† over there. He carried his first experience of feeling what death is like. This was the story he wrote at the end of the novel about his first love, Linda, as a nine year old dying of a brain tumor. He took this story and related it to the death of his comrades and the people he killed. It provides the reader with the experience of not just knowing about death, but living it. This book impacted United States history greatly. It provides a perspective of not just the Vietnam War, but all war. It is a testament to Americans of what life is like defending freedom, whether or not you agree with the cause. This book impacted United States history by helping finishing the story. It helps write the last few pages of what this war was about; not by filling it with more facts, but by filling it with questions, experiences, and life. This book demonstrates to Americans why views and opinions were made and also the purpose for many controversial decisions in our history. This book impacted our country’s history by giving the Vietnam War a personal touch. Without this book, Americans would be left with only facts, information, and brief explanations for what life was like for the soldiers. The Things They Carried continues to impact readers and helps give understanding of current events. Because of this, it will continue to impact United States history for generations and its importance to our nation and its history will only grow. The Things They Carried also greatly impacted history in general. It did this especially for those living in Vietnam who were impacted by the war. It shares with them the trials and tribulations that Americans encountered. The book shares with these people an emotional side to the war and helps them understand our soldiers’ many motives. On an international scale, the book helps those who question American tactics and procedures to understand our nation’s motives, principles, and character. Many mistakes were made on our country’s part during the war and this book helps those who question those mistakes and or were impacted by them a sense of understanding and mercy. This book also helps people to understand what life was like for all those who fought in wars throughout the Earth’s history. It provides a sense of understanding of what all soldiers are impacted by in war starting from the beginning of time. I have been greatly impacted by this book in both a positive and negative way. I have been positively impacted by the new sense of understanding and compassion for the Vietnam War Veterans. I can now see clearly what experiences they faced during the war. I can also understand the feelings of those who were against the war and attempted to avoid fighting in it, much like the author. Another aspect I understand better now is their lives after the war. The emotional turmoil that veterans go through once they arrive home from war can be greatly understood by reading this book. Even though it is disturbing and I find it more than sinful, I have a greater sense of understanding for those like Norman Bowker from the novel who took his own life. Even though I am highly against his action, I understand why he felt lost, empty, and purposeless on Earth after the war. Norman felt like he died in Vietnam and he struggled to find his place and purpose in life. This led to his suicide. Because O’Brien included this story, it is much easier to find compassion for someone who would do what Bowker did. After reading this book, I have a new found respect for Veterans. I have felt their emotions and their tragedies, because of the power and realism of this book and now my compassion and respect for them has heightened greatly. The book also impacted me in a negative way. I hate to ever imagine that the things described in the book ever happened, but this book made these things a reality for me. Many of the tales told in this book are very disturbing and horrifying. Though without the truthfulness and realism of this book and its stories, we would never be able to truly understand what happened to those who served in the Vietnam War. I am forever grateful for reading this book. All Americans need to read it. Without it, they will never be able to understand what the Vietnam War Veterans truly went through in Vietnam and what horrible memories they are faced with remembering today. Tim O’Briens talent as a writer is what makes this novel such a compelling and eye opening experience. The Things They Carried is truly an American timepiece and a pivotal piece of American and historical literature. The Things They Carried OutlineLiterature Summary: â€Å"The Things They Carried†, published in 1990 tells a true story of Tim O’Brian, author and main character, who is drafted for the Vietnam war. He tells about the different items that him and his fellow soldiers carried with them to help cope with the traumatic environment that they were placed in.Thesis Statement: com/tim-obrien-the-things-they-carried-and-his-writing-style/">The Things They Carried is a perfect example that shows that post-traumatic stress disorder (PTSD) is an issue as old as war, only recently have we discovered its true effects on our servicemen and women, and we have yet to find a truly effective remedy. I. What are the causes of PTSD?A. Tony Dokoupil claims â€Å"moral injury† is the leading cause of PTSD. B. Robert Burns says army suicides are way to high. II. How current treatment for PTSD is failing? A. Lindsey Tanner reveals that dangerous painkillers are given to vulnerable veterans. B. Tony Dokoupil exa mines the changes in a group of veterans once they return from battle. III. How could treatment be better?A. William Becker shares his belief on the ideal treatment. B. What is our job as civilians for our veterans? PTSD: An Epidemic Does America Need to Improve Treatment?Most Americans know that post-traumatic stress disorder (PTSD) is something that effects veterans when they come back from war. However, most Americans don’t know the full extent of PTSD in a veteran’s life. There are some very serious effects of war that change the lives of veterans and those close to them. Most soldiers want to protect their country and still make it home alive. This sometimes forces an innocent man to do things that he is ashamed of.Also, just the trauma and risk of being in a war can cause a man to be changed drastically when he returns from war. The treatment for this common disorder is lacking effectiveness. In some cases veterans end up being worse after finishing treatment and others just cover up their guilt and sadness with prescription drugs. Being one of the most advanced countries in the world it is only reasonable that America could find a better way to treat this devastating syndrome. It is the least American citizens can do for sending thousands of troops into a traumatic situation.The Things They Carried is a perfect example that shows that post-traumatic stress disorder (PTSD) is an issue as old as war, only recently have we discovered its true effects on our servicemen and women, and we have yet to find a truly effective remedy. In the book The Things They Carried Lieutenant Jimmy Cross feels guilty because he believes that he is not the leader that the men in his company need (1990). Tony Dokoupil also discusses this in his article, â€Å"Moral Injury†, by stating that recent studies have discovered that guilt may be a major factor of PTSD.Dokoupil talks about a group of marine preservatives, the Saints and the Sinners. He explains how Fox Company, members of The Saints and the Sinners, were walking through the streets of Baghdad when their radio operator was shot in the head. Fox Company began taking heavy fire, so they started shooting at everything that moved. Instantly bullets rained down and a grenade even bounced behind their cover. However it was a dud. Tony claims that â€Å"moral injury† is the leading cause of PTSD. Most marines talk about guilt, shame, or regret, not about being scared.Dokoupil continues to write about Lu Lobello who was a machine gunner in Fox Company. When Lobello talked to a group of people about his experience, he revealed that they had killed about 20 civilians that particular day in Baghdad. Lobello describes the many cars holding families in them that were lifeless after the firefight. His most disturbing image of that day was a fellow marine who turned to Lobello and screamed, â€Å"We shot a baby† (as cited in Dokoupil, 2012)! Dokoupil explains that marines arenà ¢â‚¬â„¢t scared, they feel guilty and regretful (2012).In Robert Burns article, â€Å"Military Suicides are at a Record High†, he stresses â€Å"Suicides in the U. S. Military surged to a record 349 last year. † Burns explains that not only is this number way too high, but is 48 suicides more than the year before (2012). Warren Kinghorn, a psychiatrist at the Department of Veteran Affairs (VA), stresses that in 2012, suicide was a greater cause of death than combat for Army soldiers. â€Å"An estimated 10%-20% of returning combat veterans meet criteria for PTSD,† says Kinghorn.She explains that when a veteran  walks into the VA, the treatment often involves a short-term talk therapy course and medication. â€Å"That is far from enough†, Kinghorn expresses. The definition of PTSD is having â€Å"experienced, witnessed, or (have) been confronted with death or serious injury in oneself or others. † This is very misleading because most veterans suffe r due to taking the life of other human beings. Shira Maguen, a psychologist at the San Francisco VA Medical Center, has documented that PTSD is worse and thoughts of suicide are higher among veterans who have killed someone (as cited in Kinghorn, 2012).  (2012)According to an article by Lindsey Tanner, a government study claims that pain killers such as morphine are being prescribed to veterans who suffer from physical pain along with PTSD, and the results are often dangerous. The same study mentions that not only are these veterans prone to drug and alcohol abuse but they are twice as likely to be prescribed addictive pain killers over veterans with only physical pain. Along with addiction, suicides, and other self inflicted injuries, are more common for veterans with PTSD who received those drugs.Michael Von Korff, a chronic illness researcher, stresses that the emotional problems involved in PTSD are often made worse by these opioids (as cited in Tanner, 2012). Tanner goes on to say, â€Å"These prescriptions went to almost 18 percent of vets with PTSD and 12 percent of those with other mental health problems, compared to about 7 percent of vets without these problems. † Dr. William Becker, a Yale university instructor, says â€Å"The study brings much needed attention to the complexity of this problem (2012). † Tony Dokoupil’s article points out that even though Fox Company made it home alive they were changed forever.One in four of them had PTSD. The men of Fox Company tried to hide it, but careers crumbled and marriages fell apart. Dokoupil adds, â€Å"Self harm is now the leading cause of death for members of the army†¦ Every month 1,000 of them attempt to take their own lives (2012). † This is similar in the novel The Things They Carried. Tim introduces us to his daughter Kathleen, he tries to tell her the meaning of war and why we participate in it but he just cannot tell her the whole truth. Just like Fox Company T im had done things that he was ashamed of and he could not talk about them openly to his family.Which is why treatment is such an important foundation for veterans (1990). In Lindsey Tanner’s article â€Å"Vets Prone to Drug Addiction Get Risky Painkillers†, William Becker says â€Å"The ideal treatment includes behavioral counseling therapy for war wounds and management of chronic pain† (as cited in Tanner, 2012) (2012). â€Å"On Guard Against PTSD† is an article that explains that security professionals who get assigned to dangerous, stressful situations will also experience post-traumatic stress. This is normal says the article, but when this occurs continuously and intensely is when it gets dangerous.The article continues by stating that sooner or later the human body runs out of ways to cope and is overwhelmed mentally and physically, leading to PTSD (2013). Warren Kinghorn also explains in his article, â€Å"The Moral Dimensions of PTSD†, tha t as civilians it is our job to take care of the veterans and have patience with their recovery, we sent them to war in the first place, it’s the least we can do (2012). PTSD going untreated is still a current epidemic. â€Å"Gunman killed by police was Iraq vet who spoke of PTSD† is an article explaining the story of Santiago A. Cisneros III.He lived in Multnomah county and on Monday, March 4th, 2013 he opened fire on two police officers. The officers had no choice to shoot back and kill Cisneros. This Oregonian veteran had frequently talked about PTSD and how he may have it, but he never got treatment. This just shows how these men and women are expected to be tough and strong and how they can feel ashamed to ask for help (2013). â€Å"Take heart; Post-traumatic stress disorder† says that the death and suicide of too many veterans has prompted the Army to promise that seeking treatment will not affect a soldiers job.This article also says that the idea of givi ng PTSD sufferers a Purple Heart award has been tossed around among government officials. This only seems fair due to the life-changing risk that they took to end up with this dramatic disorder (2009). America should take Ted Lavender into account when they think of how not to treat PTSD. He is another character that O’Brian writes about in The Things They Carried. Sadly he dies shortly after the novel begins but up until that point he is popping tranquilizer pills to calm himself down. This illustrates the type of addiction that could occur in a veterans life (1990).Post-traumatic stress disorder is extensively described in the book The Things They Carried. It shows that PTSD is an injury that hasn’t changed in decades. The only thing that has changed is America’s knowledge of it. It has been called shell shock, battle fatigue, accident neurosis, PTSD, and even more recently it is known as â€Å"moral injury. † Even though America cannot precisely pinpoi nt what causes this disorder, the doctors who treat veterans can narrow it down by using examples of previous patients, examples such as guilt and taking another man’s life.Currently the system for treating veterans with PTSD is failing, and in some situations making patients worse, like supplying addicted veterans with drugs. Short amounts of therapy and large amounts of painkillers are not what they need. Veterans need time and support with years of talk therapy to work through the moral dimensions of PTSD. For veterans who have this disorder it is a scary and helpless situation. They deserve good quality medical care, but if America cannot find a way to better treat this dilemma then future veterans will be faced with the same trauma that previous veterans have faced for years. The Things They Carried Tim O’Brien’s novel, The Things They Carried, provides an incredible realization of what life was like for an American soldier who fought in Vietnam from perspectives before, during, and after the war. The story’s power draws you in. It makes the events in the story seem real and provides the reader with a sense of what it feels like to be one of the soldiers. O’Brien’s talent as a writer made a fictional story more than believable to the reader. When reading this book, the reader struggles with depicting what is factual and what is fictional. O’Brien provides this effect by blurring the line between reality and fantasy. The book recollects many stories from O’Brien’s own experiences as a soldier and includes fictional aspects to enhance the story and to help O’Brien get his point across. O’Brien teaches us in all of these stories that there is no difference between what is factual and what is fictional in war. By doing this, the reader experiences the feelings that O’Brien and his comrades felt. The Things They Carried describes what those men carried to battle and back home, both tangible and intangible. The novel questions what war is and what the individual soldiers received out of it. This novel is an eye opener. Any person’s perspectives on the war and its soldiers are most certainly to change after reading this book. The Things They Carried brings the Vietnam War to life like no civilian could have ever imagined. The things the soldiers carried in Vietnam were both tangible and intangible. The tangible items include the usual equipment that soldiers carry, but most important is the intangibles. This book emphasizes that the intangibles the soldiers carried influenced everything about their lives, before, during and after the war. These things included the mental and psychological weight carried by the soldiers. This weight included shame, horrid memories, death and destruction. It included relationships and personal trials and temptations. It also included the soldiers’ way of handling the war. Many soldiers described in the novel used things such as drugs, pain, or fantastical illusions to deal with the war. The author, who is the narrator, was against the war. The book displays the weight of the personal struggle that he felt as someone against what he was doing over there. Another aspect that the book describes is the inexperience that the soldiers carried. This came from their age. Most, including the author, were of 21 years of age or younger. They carried the weight of large futures being destroyed by their involvement in the war. All of these aspects put extreme emotional stress on the lives of these soldiers during and after the war. The author deals with his emotional dilemmas by wiring about the tragedies and emotions he and his comrades felt. The book is entirely based off of these things. Its purpose is to help those who were not there to understand what it felt like to be them and for us to never forget the things they carried. The Things They Carried is about death. It questions death. It asks what death feels like. It also answers these questions by pulling death up and bringing it back to life. It brings it back to life and tells its stories. These stories share with the reader what death feels like. They show the reader what death is like for you and those who care about you. The author includes this topic, because it relates to something important to him that he â€Å"carried† over there. He carried his first experience of feeling what death is like. This was the story he wrote at the end of the novel about his first love, Linda, as a nine year old dying of a brain tumor. He took this story and related it to the death of his comrades and the people he killed. It provides the reader with the experience of not just knowing about death, but living it. This book impacted United States history greatly. It provides a perspective of not just the Vietnam War, but all war. It is a testament to Americans of what life is like defending freedom, whether or not you agree with the cause. This book impacted United States history by helping finishing the story. It helps write the last few pages of what this war was about; not by filling it with more facts, but by filling it with questions, experiences, and life. This book demonstrates to Americans why views and opinions were made and also the purpose for many controversial decisions in our history. This book impacted our country’s history by giving the Vietnam War a personal touch. Without this book, Americans would be left with only facts, information, and brief explanations for what life was like for the soldiers. The Things They Carried continues to impact readers and helps give understanding of current events. Because of this, it will continue to impact United States history for generations and its importance to our nation and its history will only grow. The Things They Carried also greatly impacted history in general. It did this especially for those living in Vietnam who were impacted by the war. It shares with them the trials and tribulations that Americans encountered. The book shares with these people an emotional side to the war and helps them understand our soldiers’ many motives. On an international scale, the book helps those who question American tactics and procedures to understand our nation’s motives, principles, and character. Many mistakes were made on our country’s part during the war and this book helps those who question those mistakes and or were impacted by them a sense of understanding and mercy. This book also helps people to understand what life was like for all those who fought in wars throughout the Earth’s history. It provides a sense of understanding of what all soldiers are impacted by in war starting from the beginning of time. I have been greatly impacted by this book in both a positive and negative way. I have been positively impacted by the new sense of understanding and compassion for the Vietnam War Veterans. I can now see clearly what experiences they faced during the war. I can also understand the feelings of those who were against the war and attempted to avoid fighting in it, much like the author. Another aspect I understand better now is their lives after the war. The emotional turmoil that veterans go through once they arrive home from war can be greatly understood by reading this book. Even though it is disturbing and I find it more than sinful, I have a greater sense of understanding for those like Norman Bowker from the novel who took his own life. Even though I am highly against his action, I understand why he felt lost, empty, and purposeless on Earth after the war. Norman felt like he died in Vietnam and he struggled to find his place and purpose in life. This led to his suicide. Because O’Brien included this story, it is much easier to find compassion for someone who would do what Bowker did. After reading this book, I have a new found respect for Veterans. I have felt their emotions and their tragedies, because of the power and realism of this book and now my compassion and respect for them has heightened greatly. The book also impacted me in a negative way. I hate to ever imagine that the things described in the book ever happened, but this book made these things a reality for me. Many of the tales told in this book are very disturbing and horrifying. Though without the truthfulness and realism of this book and its stories, we would never be able to truly understand what happened to those who served in the Vietnam War. I am forever grateful for reading this book. All Americans need to read it. Without it, they will never be able to understand what the Vietnam War Veterans truly went through in Vietnam and what horrible memories they are faced with remembering today. Tim O’Briens talent as a writer is what makes this novel such a compelling and eye opening experience. The Things They Carried is truly an American timepiece and a pivotal piece of American and historical literature.

Saturday, November 9, 2019

Critical Analysis of the Liver functions and medical science The WritePass Journal

Critical Analysis of the Liver functions and medical science Introduction Critical Analysis of the Liver functions and medical science IntroductionReferences:Related Introduction The liver, with over 500 functions, is one the most significant and versatile organ of the human body. It weighs around 1.5kg and it is divided into four lobes; left, right, quadrate and caudate. It is wrapped in a fibrous capsule which is covered by the visceral peritoneum. 30% of the bloody supply of the heart reaches the liver at a region called the Hilus every minute, of which two thirds is through the portal vein and a third through the hepatic artery, it then leaves the liver through the hepatic vein. Blood pressure is low, usually at 10mm Hg or less. The cells of the liver are known as Hepatocytes. Hepatocytes serve many roles in the functions of the liver of which include:   Metabolic regulation; it plays a key role in the metabolism of carbohydrates, fats and proteins, Haematological regulation; it is the primary organ that regulates the composition of blood, and Bile synthesis. [2] During carbohydrate metabolism, most of the glucose that is derived from the breakdown of carbohydrates is stored as glycogen in the liver cells (Glycogenesis) until it is needed, which is when the liver will convert the glycogen back into glucose to be used for respiration (Glycogenolysis). Examples of such situations are when there is a short supply of glucose in the body during the times between meals or when fasting. When the body is starved from carbohydrates, the liver can produce glucose by a process called Gluconeogenesis by converting amino acids from dietary and body proteins, lactate or glycerol into glucose. This prevents the individual from having hypoglycaemia (low blood glucose levels), so by this it can also be said that the liver has an integral part of maintaining blood glucose levels. The liver serves a major role in fat metabolism by producing the lipoproteins that are needed to transport fat, cholesterol and triglycerides in the blood throughout the body. Protein metabolism takes place in the liver as it goes through amino acid conversion, most of the amino acids are synthesised into proteins that are needed for the body, especially albumin which is the main plasma protein. Amino acid metabolism however produces a waste product, Urea, which is transported to the kidneys via blood and excreted through urine. Haematological regulation is the way in which the liver processes the blood by regulating the amount of chemicals it holds and breaking down the nutrients within it so it is easy to use. It also detoxifies toxic substances such as drugs or alcohol that come via blood and breaks it down before being released back into the blood into amounts that can be handled by the body. In addition to its metabolic functions, it is also responsible for the production of bile. Bile is a yellow alkaline fluid that is produced by the hepatocytes made up of mainly water (85%) and bile salts (10%).   Bile salts acts as a fat emulsifier so it is needed for the normal digestion and absorption of ingested fats. Bile also serves as a route in which substances such as drugs and wastes produced from metabolism that aren’t removed by the kidneys, such as bilirubin, is removed from the body through the faeces. Hepatocytes secrete bile into tubes known as Bile Canaliculi, which jointo form Bile Ductules. Bile ductules then transport bile to the nearest portal area. The right and left hepatic ducts collects the bile from the ductules at the portal areas and merge to form the Common Hepatic Duct.   This leaves the liver to go to the gall bladder through the Cystic Duct which joins onto the Common Bile Duct which transports bile to the duodenum through the Duodenal Ampull a and then goes into the small intestine ready to act upon the absorption of fats. [2] These are only a few functions of the liver, all of which if do not function properly can lead to many liver diseases.   Diseases can generally be classified into two types; Hepatocellular, which results in damage to the hepatocytes and Cholestatic which restricts bile flow due to blockage in ducts. Most patients suffering from a liver disease develop jaundice resulting from high levels of the bilirubin in the blood stream (hyperbilirubinemia).   Jaundice makes whites of the eyes yellow and then gradually the skin start becoming yellow. Bilirubin is produced from dead red blood cells; at the end of their life span, the haemoglobin found within them is released and split into haem and globin. Iron from haem is recycled for the production of more haemoglobin and any remains of the haem molecule are converted to bilirubin. It is excreted in the faeces and some in the urine. It is elevated in most liver diseases as they cause some sort of damage to hepatocytes which means bilirubin cannot conjugate with glucuronic acid in order to be excreted, so it stays in the bloodstream where its levels continuously increase. One of the common diseases to occur in the liver is Hepatitis. It results in inflammation of the liver cells. Viral Hepatitis can be caused by Hepatitis A, B, C, D, E, yellow fever or Herpes Simplex. Patients usually start off small with flu like symptoms. Non viral hepatitis can be due to auto immune reasons, drugs, toxins found in mushrooms and alcohol. [3] ‘As alcohol consumption is very high in the western world, alcohol hepatitis is a common problem. Symptoms include enlargement of the liver, development of fluid in the abdomen (ascites), increased blood pressure in the portal vein and later development of jaundice. If alcoholic hepatitis is diagnosed it is important to stop consuming alcohol at once otherwise it could lead to more serious damage such as cirrhosis or even liver failure.’ [2] Cirrhosis is an irreversible liver disease. Patients with cirrhosis develop ascites, jaundice and the formation of fibrous tissue where liver cells should be, the liver cells are destroyed in response to toxic chemicals, a viral hepatitis, or most commonly, high alcohol consumption. These are examples of Hepatocellular liver diseases. An example of a Cholestatic liver disease would be Cholestasis.   Cholestasis is a state when there is a blockage in the bile ducts so bile cannot be released. Again, jaundice develops when a patient suffers from cholestasis as bilirubin is also unable to reach the small intestine to be excreted. Other symptoms include pale faeces and dark urine. There are a number of tests available that determines liver diseases. These include bilirubin, ALP, ALT and the GGT tests. A slightly abnormal bilirubin concentration indicates it may be haemolytic anaemia (abnormal rate of red blood cell destruction). A higher concentration is due to diseases which have damaged the hepatocytes therefore bilirubin cannot conjugate or be excreted properly. These diseases are acute hepatitis and alcoholic hepatitis. A very high concentration indicates cholestasis as it means bile flow is completely blocked (most commonly by gallstones) and so bilirubin cannot be excreted. Bilirubin can be measured by taking a blood test; conjugated, unconjugated or total bilirubin. Conjugated bilirubin is bound to glucuronic acid and so is called direct bilirubin. Unconjugated bilirubin is measured by subtracting the direct bilirubin from the total bilirubin, so is called indirect bilirubin. Total Bilirubin is the term used when both are measured. GGT, ALP and ALT are all enzymes that are present in the liver cells. Hepatocyte death (necrosis) leads to large amounts of these enzymes to be released into the blood stream which if measured will serve as an indicator of liver disease. These enzymes can be measured by taking around 5 ml of venous blood. Abnormal ALT (alanine transferase) results are found in diseases that have come about as a result of necrosis. In acute hepatitis, ALT rises before jaundice develops and then usually goes back to normal within 8 weeks. A continuous raised level of ALT means that it chronic liver disease such as chronic hepatitis or cirrhosis. High GGT (gamma glutamyl transferase) levels are found in all liver and biliary tract diseases. GGT doesn’t determine an actual disease but it is used to predict who may be at risk of liver disease due to alcohol as it is the only enzyme that is produced due to alcohol, so high continuous levels would mean alcoholic hepatitis or cirrhosis. Moderately results of ALP (alkaline phosphatise) indicate acute hepatitis but extremely high results show cholestasis may have developed. However, ALP is also present in the cells of the bone, so only measuring it by itself would not be an accurate indication of liver disease. It is usually measured alongside GGT; if both levels are high then it confirms that the problem is definitely within the liver. These are a few diseases and tests that are commonly used today to identify one of the biggest causes of death in the UK today. References: [1] Martini, F., H., 2004, Fundamentals of Anatomy and Physiology, 6th edition, San Francisco: Benjamin Cummings, ISBN: 0-13-120346-0. [2] Higgins, C., 2000, Understanding Laboratory Investigations, Oxford: Blackwell Science Ltd, ISBN: 0-632-04245-1 [3] Mayo Clinic Staff, 2010, Alcoholic Hepatitis, Mayo Clinic, DS00785

Wednesday, November 6, 2019

Free Essays on Age Of The Baroque

The word Renaissance means â€Å"rebirth†. The idea of rebirth originated in the belief that Europeans had rediscovered the superiority of Greek and Roman culture after many centuries of what they considered intellectual and cultural decline. The preceding era became known as the Middle Ages to indicate its position between the classical and modern world. The Renaissance represents a change in focus and emphasis from the Middle Ages. Philosophy in the Renaissance changed the way people looked at humanity, the Roman Catholic Church, and their lives. Before the Renaissance the paradigm was to be humble, chaste, and obedient. However, with the start of the Renaissance, the paradigm shifts to wit, subversion, and sophistication. People began to look at themselves and see more that subservient humans. The Roman Catholic Church was at its height in 1300 A.D. This was about the time that the Renaissance started. During the Renaissance the people grew tired of the strictness and controlling nature of the Church. They decided it was time to have less rules and more fun. Instead of focusing their time on one subject, they decided to be more â€Å"well-rounded† individual, which knowledge in many different areas. Writers had a great deal of influence on the Renaissance movement and the people in it. Which brings us to one of the most influential writers of all times, William Shakespearse. One of the greatest struggles Hamlet has through the whole drama, is his indecision about what he should do. That was what was driving him mad. He was fighting with his character. To let things remain as they are or to try to change them. As in life, sometimes we find it easier to just go with the status quo and not rock the boat. Or we come face to face with situation in our lives that require us the make decisions that affect the rest of our lives. In the beginning, Hamlet had many opportunities to avenge his father’s death but just killin... Free Essays on Age Of The Baroque Free Essays on Age Of The Baroque The word Renaissance means â€Å"rebirth†. The idea of rebirth originated in the belief that Europeans had rediscovered the superiority of Greek and Roman culture after many centuries of what they considered intellectual and cultural decline. The preceding era became known as the Middle Ages to indicate its position between the classical and modern world. The Renaissance represents a change in focus and emphasis from the Middle Ages. Philosophy in the Renaissance changed the way people looked at humanity, the Roman Catholic Church, and their lives. Before the Renaissance the paradigm was to be humble, chaste, and obedient. However, with the start of the Renaissance, the paradigm shifts to wit, subversion, and sophistication. People began to look at themselves and see more that subservient humans. The Roman Catholic Church was at its height in 1300 A.D. This was about the time that the Renaissance started. During the Renaissance the people grew tired of the strictness and controlling nature of the Church. They decided it was time to have less rules and more fun. Instead of focusing their time on one subject, they decided to be more â€Å"well-rounded† individual, which knowledge in many different areas. Writers had a great deal of influence on the Renaissance movement and the people in it. Which brings us to one of the most influential writers of all times, William Shakespearse. One of the greatest struggles Hamlet has through the whole drama, is his indecision about what he should do. That was what was driving him mad. He was fighting with his character. To let things remain as they are or to try to change them. As in life, sometimes we find it easier to just go with the status quo and not rock the boat. Or we come face to face with situation in our lives that require us the make decisions that affect the rest of our lives. In the beginning, Hamlet had many opportunities to avenge his father’s death but just killin...

Monday, November 4, 2019

Compare and contrast Research Paper Example | Topics and Well Written Essays - 750 words - 1

Compare and contrast - Research Paper Example For example, in a car petrol/gas (energy) is the forward movement. Without it, the vehicle cannot move, may be the best model, with the ablest chauffeur behind the wheel! It has been pre-ordained that the car will move only with the source of energy. The driver at the wheel forms part of the lateral movement. He can drive the vehicle, fast, slow, he can choose the ideal route as per his choice, if the vehicle unfortunately hits the divider he is responsible—meaning thereby, he has the free choice as for movements of the car. In the present story, Oedipus executes his actions of his free will. He makes the independent choices.†To what extent can anybody enjoy freewill? To what extents are we too the children of chance?†Ã¢â‚¬â€all these questions are analyzed in this drama. (Knox, 1994, Back Matter) Take one such example of freewill in the play regarding the punishment proposed to be meted out to King Laiaus’s killer. Oedipus asserts that he curses the killer to live in exile. This shows how he exercises his free will. He could have as well put the killer to death or ordered his imprisonment. Another example when Oedipus exercises his free will is when he inflicts self-punishment of blinding himself. The reason for this action is he comes to know that Jocasta is his mother and the individual he killed long ago, Lauis, is his father. He kills his father and marries his mother! When he realizes his cruel folly, it is too much for him to bear. He decides to punish himself severely. In the exercise of his free will he doesn’t care for the consequences. Instead of stabbing his eyes, he could have owned responsibility for his evil actions but he exercises his free will for self-punishment. Exercising free will doesn’t mean, one is assured of success in life always. We are told by Bernard Knox, â€Å"At the center of drama is Oedipus with his absolute determination to know the truth. He dominates from beginning to end. The paradox which divides interpreters and

Saturday, November 2, 2019

Governance and Business Strategy Essay Example | Topics and Well Written Essays - 1500 words

Governance and Business Strategy - Essay Example It leads to the expansion of the hidden economy not only not only because of tax rates or social security rates, but for the arbitrary and inefficient implementation of regulatory and tax regimes in the economy with the existence of corruption. Having implications on the various aspects of the economy, the present project seeks to bring forth these implications of corruption in the economy. Critical reviews are provided with regards to the implications of corruption on the economic development of a nation (CSD, 2005, p.73). Corruption and Economic Development-Critical Analysis The empirical and theoretical debate on the effects of corruption on the economic development of nations remains unclear and unresolved. Available nationwide evidences show that the economic implications of corruption on economic development of nations can be either positive or negative. Previous empirical literature has tried to explore the relationship between corruption and development in great detail and ha s come up with surprising results. It is seen that corruption affects developing and developed countries differently. This is on account of the fact they differ significantly in terms of their economic and cultural characteristics but are plagued by similar levels of corruption in their economies (Kutan, Douglas & Judge, n.d., p.2). Some researchers have argued over the fact that corruption has negative effects on the economic development of nations as it redirects the nation’s resources into unproductive directions and consequently distorts the normal functioning of the economy. Tanzi and Davoodi (1997) has out firth four different channels through which corruption can have damaging implications over the economic growth of nations. These are high public investments; low revenue by the government; low expenses on business maintenance and operations and; poor quality of public infrastructure. On the other hand, some researchers have declared that corruption can be economically favourable in certain nations under certain circumstances as it triggers efficient government services in the form of bypassing such aspects like inefficient regulations and red tapes (Kutan, Douglas & Judge, n.d., p.3). Bureaucratic corruption can also be influenced by economic development. This is considered to be two-way causality and can be demonstrated through threshold effects as well as multiple equilibrium which form grounds for varying incidence of corruption across different countries (Blackburn, Bose & Haque, 2005, p.21). Implications of corruption on the economic activities are studied from many different perspectives. Mauro (1995), has tried to identify the effects of corruption and various other institutional factors includes red tapes, efficiency of the judicial system, political stability on the economic development of 67 nations across the world between the period 1980 and 1983. This analysis revealed that corruption reduced private investments considerably. Influe ncing investments corruption alters the composition of the government expenditures particularly reducing its share on its spending on education in the economy. Research conducted by Tanzi and Davoodi (1997) revealed that high corruption causes higher public investments, low revenues for the government, low expenditures on maintenance and o